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Given that this condition is usually treated after birth, this suggests that the higher AQ scores in such children reflect elevated prenatal androgen levels.
However, these findings should be interpreted with caution, because CAH carries a number of related problems (and requires extensive treatment) which may affect the atypical cognitive profiles found in this population .
Sex differences were observed in Q-CHAT scores, with boys scoring significantly higher (indicating more autistic traits) than girls.
In addition, we confirmed a significant positive relationship between FT levels and autistic traits.
Recent research has suggested that ASC represent the upper extreme of a collection of traits that are continuously distributed in the population .
Written informed consent was obtained from general practitioners (GPs) and participating parents.The consistency of findings in early childhood, later childhood and adulthood suggests that this is a robust association.Autism, high-functioning autism, Asperger syndrome (AS) and pervasive developmental disorder not otherwise specified (PDD-NOS) are collectively referred to as autism spectrum conditions (ASC).These patterns have also been observed in the siblings and parents of children with ASC, indicating the possibility of a link between genetically based elevated FT levels and the development of ASC .Other evidence of a genetic link to ASC was provided by a recent study, which showed that genes regulating sex steroids are associated with autistic traits, as measured by scores on the Autism Spectrum Quotient (AQ), in a typical adult sample .